Synapsin: Difference between revisions

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'''Synapsins''' (SYN) are neuronal phosphoproteins which modulate neurotransmitter release at the pre-synaptic terminal by reversibly tethering synaptic vescicles to the actin cytoskeleton<ref>PMID:20438797</ref>.
'''Synapsins''' (SYN) are neuronal phosphoproteins which modulate neurotransmitter release at the pre-synaptic terminal by reversibly tethering synaptic vescicles to the actin cytoskeleton<ref>PMID:20438797</ref>.
*'''Synapsin 1''' is involved in synapse formation<ref>PMID:9513186</ref>.
*'''Synapsin 1''' is involved in synapse formation<ref>PMID:9513186</ref>.
*'''Synapsin 2''' is involved in axon formation
*'''Synapsin 2''' is involved in axon formation.
*'''Synapsin 3''' is involved in regulation of dopaminergic neurotransmission<ref>PMID:21827867</ref>.


== Structural highlights ==
== Structural highlights ==

Latest revision as of 07:47, 15 August 2024

Rat synapsin 1 complex with ATP and Ca++ ion (green) (PDB code 1px2)

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Michal Harel, Alexander Berchansky