Syntaxin: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 6: | Line 6: | ||
*'''Stx-1''' is essential for the formation of the SNARE complex involved in the fusion machinery in the brain. Stx-1 forms a 4-helical bundle complex with proteins SNAP-25 and VAMP2 which drives fusion of vesicles with the plasma membrane<ref>PMID:26903802</ref>. The coiled-coil bundle structure is formed by the interactions of the complex SNARE motifs<ref>PMID:24218570</ref>. | *'''Stx-1''' is essential for the formation of the SNARE complex involved in the fusion machinery in the brain. Stx-1 forms a 4-helical bundle complex with proteins SNAP-25 and VAMP2 which drives fusion of vesicles with the plasma membrane<ref>PMID:26903802</ref>. The coiled-coil bundle structure is formed by the interactions of the complex SNARE motifs<ref>PMID:24218570</ref>. | ||
*'''Stx-1A''' regulates the function of transmembrane proteins like ion channels and neurotransmitter transporters<ref>PMID:18617632</ref>. | *'''Stx-1A''' regulates the function of transmembrane proteins like ion channels and neurotransmitter transporters<ref>PMID:18617632</ref>. | ||
*'''Stx-6''' is a SNARE protein involved in a variety of internal membrane fusion events. | |||
*'''Stx-7''' is involved in endosomal membrane fusion<ref>PMID:34408265</ref>. | |||
*'''Stx-10''' is a SNARE protein localised to the trans-Golgi network<ref>PMID:16154903</ref>. | |||
*'''Stx-12''' is a SNARE protein localised to the endosome<ref>PMID:9507000</ref>. | |||
*'''Stx-13''' has a role in membrane expansion during neuronal development <ref>PMID:10886332</ref>. | |||
*'''Stx-17''' is required for autophagosome-lysosome fusion<ref>PMID:23466629</ref>. | |||
*'''Stx-VAM3P''' is involved invacuolar assembly<ref>PMID:9202390</ref>. | |||
== Relevance == | == Relevance == | ||
