9cz9: Difference between revisions
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==Structure of thioferritin with averaged iron mineral core, from Pyrococcus furiosis== | |||
<StructureSection load='9cz9' size='340' side='right'caption='[[9cz9]], [[Resolution|resolution]] 2.43Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9cz9]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CZ9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.43Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9cz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9cz9 OCA], [https://pdbe.org/9cz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9cz9 RCSB], [https://www.ebi.ac.uk/pdbsum/9cz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cz9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DPS_PYRFU DPS_PYRFU] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It efficiently oxidizes Fe(2+) in the presence of hydrogen peroxide and stores it. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pyrococcus furiosus]] | |||
[[Category: Bothner B]] | |||
[[Category: Douglas T]] | |||
[[Category: Gauvin CC]] | |||
[[Category: Lawrence CM]] | |||
[[Category: Tokmina-Lukaszewska M]] | |||
[[Category: Waghwani HK]] | |||
Latest revision as of 05:28, 6 August 2025
Structure of thioferritin with averaged iron mineral core, from Pyrococcus furiosis
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