9h2d: Difference between revisions
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==Human IFT172 C-terminal U-box domain crystal structure== | |||
<StructureSection load='9h2d' size='340' side='right'caption='[[9h2d]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9h2d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9H2D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9H2D FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.097Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9h2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9h2d OCA], [https://pdbe.org/9h2d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9h2d RCSB], [https://www.ebi.ac.uk/pdbsum/9h2d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9h2d ProSAT]</span></td></tr> | ||
[[Category: Bhogaraju | </table> | ||
[[Category: Lorentzen | == Disease == | ||
[https://www.uniprot.org/uniprot/IF172_HUMAN IF172_HUMAN] Bardet-Biedl syndrome;Jeune syndrome;Retinitis pigmentosa;Saldino-Mainzer syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IF172_HUMAN IF172_HUMAN] Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Bhogaraju S]] | |||
[[Category: Lorentzen E]] | |||
[[Category: Zacharia NK]] | |||
Latest revision as of 06:22, 4 December 2024
Human IFT172 C-terminal U-box domain crystal structure
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