9k3h: Difference between revisions
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New page: '''Unreleased structure''' The entry 9k3h is ON HOLD Authors: Feng, W.B., Zhou, Q.T. Description: Cryo-EM structure of the ligand-free human melanocortin receptor 5 (MC5R)-Gs complex [... |
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==Cryo-EM structure of the unliganded human melanocortin receptor 5 (MC5R)-Gs complex== | |||
<StructureSection load='9k3h' size='340' side='right'caption='[[9k3h]], [[Resolution|resolution]] 2.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9k3h]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9K3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9K3H FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.86Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9k3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9k3h OCA], [https://pdbe.org/9k3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9k3h RCSB], [https://www.ebi.ac.uk/pdbsum/9k3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9k3h ProSAT]</span></td></tr> | ||
[[Category: Feng | </table> | ||
[[Category: Zhou | == Function == | ||
[https://www.uniprot.org/uniprot/MC5R_HUMAN MC5R_HUMAN] Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Feng WB]] | |||
[[Category: Wang MW]] | |||
[[Category: Yang DH]] | |||
[[Category: Zheng C]] | |||
[[Category: Zhou QT]] | |||