9jqy: Difference between revisions

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'''Unreleased structure'''


The entry 9jqy is ON HOLD  until 2026-09-28
==Structural Insights into Selective Antagonism of TG6-129 and EP4 Prostaglandin Receptor==
 
<StructureSection load='9jqy' size='340' side='right'caption='[[9jqy]], [[Resolution|resolution]] 2.92&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9jqy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JQY FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.92&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EC5:~{N}-[[4-[(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl]carbamothioyl]-3-(4-fluorophenyl)propanamide'>A1EC5</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jqy OCA], [https://pdbe.org/9jqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jqy RCSB], [https://www.ebi.ac.uk/pdbsum/9jqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jqy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PE2R4_HUMAN PE2R4_HUMAN] Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Synthetic construct]]
[[Category: Wu CR]]
[[Category: Wu YL]]
[[Category: Xu EH]]
[[Category: Xu JY]]
[[Category: Zhang H]]
Retrieved from "https://proteopedia.org/9jqy"