9km1: Difference between revisions
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==Crystal Structure of the bromodomain of human BRD9 in complex with the inhibitor Y22077== | |||
<StructureSection load='9km1' size='340' side='right'caption='[[9km1]], [[Resolution|resolution]] 2.68Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9km1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KM1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.68Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EFZ:1-[1-[4-(imidazol-1-ylmethyl)-3,5-dimethoxy-phenyl]indolizin-3-yl]propan-1-one'>A1EFZ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9km1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9km1 OCA], [https://pdbe.org/9km1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9km1 RCSB], [https://www.ebi.ac.uk/pdbsum/9km1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9km1 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Wu | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription. | ||
[[Category: Xu | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chen Z]] | |||
[[Category: Wu X]] | |||
[[Category: Xu H]] | |||
[[Category: Xu Y]] | |||
[[Category: Zhang C]] | |||
[[Category: Zhang Y]] | |||
Latest revision as of 09:34, 6 November 2025
Crystal Structure of the bromodomain of human BRD9 in complex with the inhibitor Y22077
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