9ef3: Difference between revisions
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The entry | ==Human Hsp27 alpha-crystallin domain (84-171) in complex with a peptide mimic of its C-terminus== | ||
<StructureSection load='9ef3' size='340' side='right'caption='[[9ef3]], [[Resolution|resolution]] 2.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9ef3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EF3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ef3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ef3 OCA], [https://pdbe.org/9ef3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ef3 RCSB], [https://www.ebi.ac.uk/pdbsum/9ef3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ef3 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/HSPB1_HUMAN HSPB1_HUMAN] Autosomal dominant Charcot-Marie-Tooth disease type 2F;Distal hereditary motor neuropathy type 2. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HSPB1_HUMAN HSPB1_HUMAN] Involved in stress resistance and actin organization. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Allison TM]] | |||
[[Category: Benesch JLP]] | |||
[[Category: Gastall H]] | |||
[[Category: Laganowsky A]] | |||
Latest revision as of 04:31, 24 June 2026
Human Hsp27 alpha-crystallin domain (84-171) in complex with a peptide mimic of its C-terminus
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