9knc: Difference between revisions
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==Crystal structure of human ERRg LBD in complex with 6-nitroindole== | |||
<StructureSection load='9knc' size='340' side='right'caption='[[9knc]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9knc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KNC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EF8:6-nitro-1~{H}-indole'>A1EF8</scene>, <scene name='pdbligand=PGR:R-1,2-PROPANEDIOL'>PGR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9knc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9knc OCA], [https://pdbe.org/9knc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9knc RCSB], [https://www.ebi.ac.uk/pdbsum/9knc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9knc ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Liu J]] | |||
[[Category: Wang N]] | |||
[[Category: Xu T]] | |||
Latest revision as of 11:29, 16 April 2025
Crystal structure of human ERRg LBD in complex with 6-nitroindole
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