9h8o: Difference between revisions

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'''Unreleased structure'''


The entry 9h8o is ON HOLD
==Structure of BmrA T123C-S428C cross-linked form (apo state)==
 
<StructureSection load='9h8o' size='340' side='right'caption='[[9h8o]], [[Resolution|resolution]] 4.26&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9h8o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9H8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9H8O FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.26&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9h8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9h8o OCA], [https://pdbe.org/9h8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9h8o RCSB], [https://www.ebi.ac.uk/pdbsum/9h8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9h8o ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BMRA_BACSU BMRA_BACSU] An efflux transporter able to transport Hoechst 33342, ethidium bromide, doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation (PubMed:18215075). Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable).<ref>PMID:18215075</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Coureux P-D]]
[[Category: Di Cesare M]]
[[Category: Hanssen E]]
[[Category: Jault J-M]]
[[Category: Kaplan E]]
[[Category: Orelle C]]
[[Category: Valimehr S]]
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