9mf1: Difference between revisions

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New page: '''Unreleased structure''' The entry 9mf1 is ON HOLD Authors: Description: Category: Unreleased Structures
 
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'''Unreleased structure'''


The entry 9mf1 is ON HOLD
==Crystal structure of RIT1 in the GDP state==
 
<StructureSection load='9mf1' size='340' side='right'caption='[[9mf1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9mf1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MF1 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mf1 OCA], [https://pdbe.org/9mf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mf1 RCSB], [https://www.ebi.ac.uk/pdbsum/9mf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mf1 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/RIT1_HUMAN RIT1_HUMAN] Noonan syndrome. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/RIT1_HUMAN RIT1_HUMAN] Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.<ref>PMID:15632082</ref> <ref>PMID:23791108</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bonsor DA]]
[[Category: Dharmaiah S]]
[[Category: Simanshu DK]]
Retrieved from "https://proteopedia.org/9mf1"