9kzc: Difference between revisions
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==Cryo-EM structure of the LGI1 LRR-LGI1 EPTP-ADAM22 ECD complex== | |||
<StructureSection load='9kzc' size='340' side='right'caption='[[9kzc]], [[Resolution|resolution]] 2.78Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9kzc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KZC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.78Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kzc OCA], [https://pdbe.org/9kzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kzc RCSB], [https://www.ebi.ac.uk/pdbsum/9kzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kzc ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ADA22_HUMAN ADA22_HUMAN] Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.<ref>PMID:12589811</ref> <ref>PMID:15882968</ref> <ref>PMID:16385342</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Fukai S]] | |||
[[Category: Kubota M]] | |||
[[Category: Mitsumori A]] | |||
[[Category: Okatsu K]] | |||
[[Category: Yamagata A]] | |||
[[Category: Yamaguchi T]] | |||
Latest revision as of 06:20, 25 June 2025
Cryo-EM structure of the LGI1 LRR-LGI1 EPTP-ADAM22 ECD complex
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