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'''Unreleased structure'''


The entry 9mjg is ON HOLD
==Crystal structure of HAT1 in complex with XS380871==
 
<StructureSection load='9mjg' size='340' side='right'caption='[[9mjg]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
Authors: Zeng, H., Li, F., Wang, X., Sun, J., Dong, A., Peng, H., Arrowsmith, C.H., Edwards, A.M., Halabelian, L., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9mjg]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MJG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MJG FirstGlance]. <br>
Description: Crystal structure of HAT1 in complex with XS380871
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.58&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1BLX:(4S,7R)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-7-(4-fluorophenyl)-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione'>A1BLX</scene></td></tr>
[[Category: Edwards, A.M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mjg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mjg OCA], [https://pdbe.org/9mjg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mjg RCSB], [https://www.ebi.ac.uk/pdbsum/9mjg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mjg ProSAT]</span></td></tr>
[[Category: Wang, X]]
</table>
[[Category: Peng, H]]
== Function ==
[[Category: Arrowsmith, C.H]]
[https://www.uniprot.org/uniprot/A0AAG2UVM1_HUMAN A0AAG2UVM1_HUMAN] Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).[PIRNR:PIRNR038084]
[[Category: Sun, J]]
__TOC__
[[Category: Li, F]]
</StructureSection>
[[Category: Dong, A]]
[[Category: Homo sapiens]]
[[Category: Zeng, H]]
[[Category: Large Structures]]
[[Category: Halabelian, L]]
[[Category: Arrowsmith CH]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Dong A]]
[[Category: Edwards AM]]
[[Category: Halabelian L]]
[[Category: Li F]]
[[Category: Peng H]]
[[Category: Sun J]]
[[Category: Wang X]]
[[Category: Zeng H]]
Retrieved from "https://proteopedia.org/9mjg"