GLP-1: Difference between revisions

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'''Glucagon-like peptide 1''' (GLP-1) is a hormone involved in insulin regulation. It was discovered when researchers found that glucose in the digestive tract led to higher insulin levels than the same amount of glucose administered directly in the blood stream<ref>PMID: 31767182</ref>. GLP-1 is produced in specialized cells in the intestine and in the pancreas, is released into the blood and has effects on cells in the pancreas, in the brain, and in many other organs. The half-life of GLP-1 is on the order of minutes, so it exerts a short-term effect unless continuously produced.

'''Glucagon-like peptide 1''' (GLP-1) is a hormone involved in insulin regulation. It was discovered when researchers found that glucose in the digestive tract led to higher insulin levels than the same amount of glucose administered directly in the blood stream<ref>PMID: 31767182</ref>. GLP-1 is produced in specialized cells in the intestine and in the pancreas, is released into the blood and has effects on cells in the pancreas, in the brain, and in many other organs. The half-life of GLP-1 is on the order of minutes, so it exerts a short-term effect unless continuously produced.

For '''Glucagon-like peptide 2''' (GLP-2) see [[Glucagon-like peptide 2]])

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

[[1dor]] - hGLP-1 residues 7-36 - human - NMR

[[6vcb]], [[6x18]], [[7duq]], [[9ivg]] - hGLP-1 + GLP-1 receptor + Gs complex + nanobody - Cryo EM

[[1dor]], [[4apd]] - hGLP-1 residues 7-36 - human - NMR

[[9x22]] - hGLP-1 + GLP-1 receptor + Gs complex - Cryo EM

[[9x20]] - hGLP-1 + GLP-1 receptor + Gs complex + ScfV - Cryo EM

[[6vcb]], [[6x18]], [[7duq]], [[9ebo]], [[9ivg]], [[9ivm]] - hGLP-1 + GLP-1 receptor + Gs complex + nanobody - Cryo EM

[[2l63]], [[2l64]] - hGLP-2 residues 146-178 - NMR

</StructureSection>

== Student contributors ==

This page was created as a two-week project of an undergraduate biochemistry course. Karsten Theis would like to acknowledge contributors Jamie, ~~Trey~~, Spencer J. Edwards, Pam, Summer, and ~~Hyancinth~~ Osei.

This page was created as a two-week project of an undergraduate biochemistry course. Karsten Theis would like to acknowledge contributors Jamie, Travon Patterson, Spencer J. Edwards, Pam, Summer, and Hyacinth Osei.

== References ==

[[Category:Topic Page]]

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@@ Line 1: / Line 1: @@
-'''Glucagon-like peptide 1''' (GLP-1) is a hormone involved in insulin regulation. It was discovered when researchers found that glucose in the digestive tract led to higher insulin levels than the same amount of glucose administered directly in the blood stream<ref>PMID: 31767182</ref>. GLP-1 is produced in specialized cells in the intestine and in the pancreas, is released into the blood and has effects on cells in the pancreas, in the brain, and in many other organs. The half-life of GLP-1 is on the order of minutes, so it exerts a short-term effect unless continuously produced.
+'''Glucagon-like peptide 1''' (GLP-1) is a hormone involved in insulin regulation. It was discovered when researchers found that glucose in the digestive tract led to higher insulin levels than the same amount of glucose administered directly in the blood stream<ref>PMID: 31767182</ref>. GLP-1 is produced in specialized cells in the intestine and in the pancreas, is released into the blood and has effects on cells in the pancreas, in the brain, and in many other organs. The half-life of GLP-1 is on the order of minutes, so it exerts a short-term effect unless continuously produced.<br />
+For '''Glucagon-like peptide 2''' (GLP-2) see [[Glucagon-like peptide 2]])
 <StructureSection size='340' side='right' scene='10/1067195/Glp1_only/1'>
@@ Line 26: / Line 27: @@
 Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-[[1dor]] - hGLP-1 residues 7-36 - human - NMR<br />
-[[6vcb]], [[6x18]], [[7duq]], [[9ivg]] - hGLP-1 + GLP-1 receptor + Gs complex + nanobody - Cryo EM<br />
+[[1dor]], [[4apd]] - hGLP-1 residues 7-36 - human - NMR<br />
+[[9x22]] - hGLP-1 + GLP-1 receptor + Gs complex - Cryo EM<br />
+[[9x20]] - hGLP-1 + GLP-1 receptor + Gs complex + ScfV - Cryo EM<br />
+[[6vcb]], [[6x18]], [[7duq]], [[9ebo]], [[9ivg]], [[9ivm]] - hGLP-1 + GLP-1 receptor + Gs complex + nanobody - Cryo EM<br />
 [[2l63]], [[2l64]] - hGLP-2 residues 146-178 - NMR<br />
 </StructureSection>
 == Student contributors ==
-This page was created as a two-week project of an undergraduate biochemistry course. Karsten Theis would like to acknowledge contributors Jamie, Trey, Spencer J. Edwards, Pam, Summer, and Hyancinth Osei.
+This page was created as a two-week project of an undergraduate biochemistry course. Karsten Theis would like to acknowledge contributors Jamie, Travon Patterson, Spencer J. Edwards, Pam, Summer, and Hyacinth Osei.
 == References ==
 <references/>
 [[Category:Topic Page]]