9lda: Difference between revisions
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New page: '''Unreleased structure''' The entry 9lda is ON HOLD Authors: Description: Category: Unreleased Structures |
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The | ==The complex structure of K63A/5'-p-ADPR-DNA== | ||
<StructureSection load='9lda' size='340' side='right'caption='[[9lda]], [[Resolution|resolution]] 2.33Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9lda]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LDA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LDA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EJJ:[[(2~{R},3~{S},4~{R},5~{S})-5-(4-azanyl-5~{H}-pyrrolo[3,2-d]pyrimidin-7-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2~{R},3~{S},4~{R},5~{S})-3,4,5-tris(oxidanyl)oxolan-2-yl]methyl+hydrogen+phosphate'>A1EJJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lda OCA], [https://pdbe.org/9lda PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lda RCSB], [https://www.ebi.ac.uk/pdbsum/9lda PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lda ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KPTA_THEKO KPTA_THEKO] Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Thermococcus kodakarensis KOD1]] | |||
[[Category: Cao CL]] | |||
[[Category: Gan JH]] | |||
[[Category: Yang J]] | |||
[[Category: Zhang WZ]] | |||
Latest revision as of 07:33, 12 November 2025
The complex structure of K63A/5'-p-ADPR-DNA
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