9mqo: Difference between revisions
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==Crystal structure of BCMA in complex with CA10v2 Fab== | |||
<StructureSection load='9mqo' size='340' side='right'caption='[[9mqo]], [[Resolution|resolution]] 3.18Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9mqo]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MQO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.181Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mqo OCA], [https://pdbe.org/9mqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mqo RCSB], [https://www.ebi.ac.uk/pdbsum/9mqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mqo ProSAT]</span></td></tr> | ||
[[Category: Qiu | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.<ref>PMID:10903733</ref> <ref>PMID:10801128</ref> <ref>PMID:10973284</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Qiu Y]] | |||
Latest revision as of 09:19, 14 January 2026
Crystal structure of BCMA in complex with CA10v2 Fab
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