9mun: Difference between revisions
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New page: '''Unreleased structure''' The entry 9mun is ON HOLD Authors: Gad, M., Hite, R.K. Description: Structure of Human SLC33A1 in complex with oxidized glutathione [[Category: Unreleased St... |
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==Structure of Human SLC33A1 in complex with oxidized glutathione== | |||
<StructureSection load='9mun' size='340' side='right'caption='[[9mun]], [[Resolution|resolution]] 3.26Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9mun]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MUN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.26Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDS:OXIDIZED+GLUTATHIONE+DISULFIDE'>GDS</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mun OCA], [https://pdbe.org/9mun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mun RCSB], [https://www.ebi.ac.uk/pdbsum/9mun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mun ProSAT]</span></td></tr> | ||
[[Category: Gad | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/ACATN_HUMAN ACATN_HUMAN] Congenital cataract-hearing loss-severe developmental delay syndrome;Autosomal dominant spastic paraplegia type 42. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACATN_HUMAN ACATN_HUMAN] Acetyl-CoA transporter that mediates active acetyl-CoA import through the endoplasmic reticulum (ER) membrane into the ER lumen where specific ER-based acetyl-CoA:lysine acetyltransferases are responsible for the acetylation of ER-based protein substrates, such as BACE1 (PubMed:20826464, PubMed:24828632). Necessary for O-acetylation of gangliosides (PubMed:9096318).<ref>PMID:20826464</ref> <ref>PMID:24828632</ref> <ref>PMID:25402622</ref> <ref>PMID:9096318</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Gad M]] | |||
[[Category: Hite RK]] | |||
