9mxk: Difference between revisions
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New page: '''Unreleased structure''' The entry 9mxk is ON HOLD Authors: Patel, K., Pachl, P., Mackay, J.P. Description: BRD4-BD1 in complex with cyclic peptide 4.1C [[Category: Unreleased Struct... |
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==BRD4-BD1 in complex with cyclic peptide 4.1C== | |||
<StructureSection load='9mxk' size='340' side='right'caption='[[9mxk]], [[Resolution|resolution]] 1.73Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9mxk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MXK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mxk OCA], [https://pdbe.org/9mxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mxk RCSB], [https://www.ebi.ac.uk/pdbsum/9mxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mxk ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Pachl | == Disease == | ||
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Mackay JP]] | |||
[[Category: Pachl P]] | |||
[[Category: Patel K]] | |||
Latest revision as of 06:24, 22 April 2026
BRD4-BD1 in complex with cyclic peptide 4.1C
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