9n2i: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "9n2i" [edit=sysop:move=sysop] |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
==cryo-EM structure of GCGR-Gs complex with SRB103Q== | |||
<StructureSection load='9n2i' size='340' side='right'caption='[[9n2i]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9n2i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9N2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9N2I FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIB:ALPHA-AMINOISOBUTYRIC+ACID'>AIB</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9n2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9n2i OCA], [https://pdbe.org/9n2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9n2i RCSB], [https://www.ebi.ac.uk/pdbsum/9n2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9n2i ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Mohebali | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/GLR_HUMAN GLR_HUMAN] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Belousoff MJ]] | |||
[[Category: Mohebali N]] | |||
[[Category: Sexton PM]] | |||
[[Category: Wootten D]] | |||
[[Category: Zhang X]] | |||