1v38: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1v38.gif|left|200px]]


<!--
==Solution structure of the Sterile Alpha Motif (SAM) domain of mouse SAMSN1==
The line below this paragraph, containing "STRUCTURE_1v38", creates the "Structure Box" on the page.
<StructureSection load='1v38' size='340' side='right'caption='[[1v38]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1v38]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V38 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v38 OCA], [https://pdbe.org/1v38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v38 RCSB], [https://www.ebi.ac.uk/pdbsum/1v38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v38 ProSAT], [https://www.topsan.org/Proteins/RSGI/1v38 TOPSAN]</span></td></tr>
{{STRUCTURE_1v38|  PDB=1v38  |  SCENE= }}
</table>
 
== Function ==
'''Solution structure of the Sterile Alpha Motif (SAM) domain of mouse SAMSN1'''
[https://www.uniprot.org/uniprot/SAMN1_MOUSE SAMN1_MOUSE] Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation.<ref>PMID:15381729</ref> <ref>PMID:19923443</ref> <ref>PMID:20478393</ref> <ref>PMID:21296879</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
1V38 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V38 OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/1v38_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v38 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Goroncy A]]
[[Category: Goroncy, A.]]
[[Category: Inoue M]]
[[Category: Inoue, M.]]
[[Category: Kigawa T]]
[[Category: Kigawa, T.]]
[[Category: Kobayashi N]]
[[Category: Kobayashi, N.]]
[[Category: Koshiba S]]
[[Category: Koshiba, S.]]
[[Category: Tochio N]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Tochio, N.]]
[[Category: Yokoyama, S.]]
[[Category: Hypothetical protein]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 12:01:18 2008''
Retrieved from "https://proteopedia.org/1v38"