9lht: Difference between revisions
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==Cryo-EM structure of inhibitor E3 bound human urea transporter A2.== | |||
<StructureSection load='9lht' size='340' side='right'caption='[[9lht]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9lht]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LHT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EJ7:5-ethanoyl-~{N}-[3-(phenylsulfonylamino)phenyl]furan-2-carboxamide'>A1EJ7</scene></td></tr> | ||
[[Category: Huang | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lht OCA], [https://pdbe.org/9lht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lht RCSB], [https://www.ebi.ac.uk/pdbsum/9lht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lht ProSAT]</span></td></tr> | ||
[[Category: Liu | </table> | ||
[[Category: Sun | == Function == | ||
[https://www.uniprot.org/uniprot/UT2_HUMAN UT2_HUMAN] Mediates the transport of urea driven by a concentration gradient across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism.<ref>PMID:11502588</ref> <ref>PMID:17702749</ref> Mediates the transport of urea driven by a concentration gradient across the cell membrane of the kidney inner medullary collecting duct which is critical to the urinary concentrating mechanism.<ref>PMID:8647271</ref> <ref>PMID:8997401</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Huang S]] | |||
[[Category: Liu L]] | |||
[[Category: Sun J]] | |||
Latest revision as of 08:21, 13 August 2025
Cryo-EM structure of inhibitor E3 bound human urea transporter A2.
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