9i9f: Difference between revisions

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'''Unreleased structure'''


The entry 9i9f is ON HOLD  until Paper Publication
==Crystal structure of apoform human eIF4A1 C-terminal domain==
 
<StructureSection load='9i9f' size='340' side='right'caption='[[9i9f]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9i9f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9I9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9I9F FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.731&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9i9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9i9f OCA], [https://pdbe.org/9i9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9i9f RCSB], [https://www.ebi.ac.uk/pdbsum/9i9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9i9f ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IF4A1_HUMAN IF4A1_HUMAN] ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.<ref>PMID:19153607</ref> <ref>PMID:19204291</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bushell M]]
[[Category: Schmidt T]]
[[Category: Turnbull AP]]
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