9ne9: Difference between revisions
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==Human polymerase epsilon bound to PCNA and DNA with a pre-existing mismatch in the blocked conformation I== | |||
<StructureSection load='9ne9' size='340' side='right'caption='[[9ne9]], [[Resolution|resolution]] 3.88Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9ne9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NE9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.88Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PST:THYMIDINE-5-THIOPHOSPHATE'>PST</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ne9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ne9 OCA], [https://pdbe.org/9ne9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ne9 RCSB], [https://www.ebi.ac.uk/pdbsum/9ne9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ne9 ProSAT]</span></td></tr> | ||
[[Category: Li | </table> | ||
[[Category: | == Disease == | ||
[https://www.uniprot.org/uniprot/DPOE1_HUMAN DPOE1_HUMAN] Facial dysmorphism - immunodeficiency - livedo - short stature. Disease susceptibility is associated with variations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DPOE1_HUMAN DPOE1_HUMAN] Participates in DNA repair and in chromosomal DNA replication. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: He Q]] | |||
[[Category: Li H]] | |||
[[Category: Wang F]] | |||
Latest revision as of 08:38, 4 June 2025
Human polymerase epsilon bound to PCNA and DNA with a pre-existing mismatch in the blocked conformation I
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