9nfs: Difference between revisions

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New page: '''Unreleased structure''' The entry 9nfs is ON HOLD Authors: Martinez Fiesco, J.A., Zhang, P. Description: Structure of J-PKAc chimera in complex with Aplithianine j1 [[Category: Unre...
 
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'''Unreleased structure'''


The entry 9nfs is ON HOLD
==Structure of J-PKAc chimera in complex with Aplithianine j1==
 
<StructureSection load='9nfs' size='340' side='right'caption='[[9nfs]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
Authors: Martinez Fiesco, J.A., Zhang, P.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9nfs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NFS FirstGlance]. <br>
Description: Structure of J-PKAc chimera in complex with Aplithianine j1
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1BX1:(4P)-4-[4-(pyrimidin-4-yl)-3,4-dihydro-2H-1,4-thiazin-6-yl]-1H-pyrrolo[2,3-b]pyridine'>A1BX1</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
[[Category: Zhang, P]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9nfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9nfs OCA], [https://pdbe.org/9nfs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9nfs RCSB], [https://www.ebi.ac.uk/pdbsum/9nfs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9nfs ProSAT]</span></td></tr>
[[Category: Martinez Fiesco, J.A]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/IPKA_HUMAN IPKA_HUMAN] Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Martinez Fiesco JA]]
[[Category: Zhang P]]
Retrieved from "https://proteopedia.org/9nfs"