9uj5: Difference between revisions

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New page: '''Unreleased structure''' The entry 9uj5 is ON HOLD Authors: Dhankhar, K., Hazra, S. Description: Crystal structure of SME-1 E166A in complex with cefprozil [[Category: Unreleased Str...
 
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'''Unreleased structure'''


The entry 9uj5 is ON HOLD
==Crystal structure of SME-1 E166A in complex with cefprozil==
 
<StructureSection load='9uj5' size='340' side='right'caption='[[9uj5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
Authors: Dhankhar, K., Hazra, S.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9uj5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UJ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UJ5 FirstGlance]. <br>
Description: Crystal structure of SME-1 E166A in complex with cefprozil
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1L87:(2~{S},5~{Z})-2-[(1~{R})-1-[[(2~{S})-2-azanyl-2-(4-hydroxyphenyl)ethanoyl]amino]-2-oxidanylidene-ethyl]-5-propylidene-2~{H}-1,3-thiazine-4-carboxylic+acid'>A1L87</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
[[Category: Dhankhar, K]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9uj5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9uj5 OCA], [https://pdbe.org/9uj5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9uj5 RCSB], [https://www.ebi.ac.uk/pdbsum/9uj5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9uj5 ProSAT]</span></td></tr>
[[Category: Hazra, S]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLAS1_SERMA BLAS1_SERMA] Class A beta-lactamase which confers resistance to the beta-lactam antibiotics, including penicillins, some cephalosporins and carbapenems, to JM109 strain E.coli (PubMed:11807251, PubMed:8092824). Acts via hydrolysis of the beta-lactam ring (PubMed:11036019, PubMed:8092824). Has penicillin-, cephalosporin- and carbapenem-hydrolyzing activities (PubMed:11036019).<ref>PMID:11036019</ref> <ref>PMID:11807251</ref> <ref>PMID:8092824</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Serratia marcescens]]
[[Category: Dhankhar K]]
[[Category: Hazra S]]
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