9uj8: Difference between revisions
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==Crystal structure of SME-1 E166A with cefovecin== | |||
<StructureSection load='9uj8' size='340' side='right'caption='[[9uj8]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9uj8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UJ8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1L9M:(2~{R},5~{R})-2-[(1~{S})-1-[[(2~{Z})-2-(2-azanyl-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-2-oxidanylidene-ethyl]-5-(4-oxidanylbutyl)-5,6-dihydro-2~{H}-1,3-thiazine-4-carboxylic+acid'>A1L9M</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9uj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9uj8 OCA], [https://pdbe.org/9uj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9uj8 RCSB], [https://www.ebi.ac.uk/pdbsum/9uj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9uj8 ProSAT]</span></td></tr> | ||
[[Category: Dhankhar | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/BLAS1_SERMA BLAS1_SERMA] Class A beta-lactamase which confers resistance to the beta-lactam antibiotics, including penicillins, some cephalosporins and carbapenems, to JM109 strain E.coli (PubMed:11807251, PubMed:8092824). Acts via hydrolysis of the beta-lactam ring (PubMed:11036019, PubMed:8092824). Has penicillin-, cephalosporin- and carbapenem-hydrolyzing activities (PubMed:11036019).<ref>PMID:11036019</ref> <ref>PMID:11807251</ref> <ref>PMID:8092824</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Serratia marcescens]] | |||
[[Category: Dhankhar K]] | |||
[[Category: Hazra S]] | |||
Latest revision as of 06:40, 22 April 2026
Crystal structure of SME-1 E166A with cefovecin
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