1vll: Difference between revisions

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[[Image:1vll.gif|left|200px]]


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==Crystal structure of alanine dehydrogenase (AF1665) from Archaeoglobus fulgidus at 2.80 A resolution==
The line below this paragraph, containing "STRUCTURE_1vll", creates the "Structure Box" on the page.
<StructureSection load='1vll' size='340' side='right'caption='[[1vll]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1vll]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VLL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VLL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vll FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vll OCA], [https://pdbe.org/1vll PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vll RCSB], [https://www.ebi.ac.uk/pdbsum/1vll PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vll ProSAT], [https://www.topsan.org/Proteins/JCSG/1vll TOPSAN]</span></td></tr>
{{STRUCTURE_1vll|  PDB=1vll  |  SCENE= }}
</table>
 
== Function ==
'''Crystal structure of alanine dehydrogenase (AF1665) from Archaeoglobus fulgidus at 2.80 A resolution'''
[https://www.uniprot.org/uniprot/ALADH_ARCFU ALADH_ARCFU] Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity.[HAMAP-Rule:MF_00935]<ref>PMID:15516582</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
1VLL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VLL OCA].  
  <jmolCheckbox>
[[Category: Alanine dehydrogenase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vl/1vll_consurf.spt"</scriptWhenChecked>
[[Category: Archaeoglobus fulgidus dsm 4304]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: JCSG, Joint Center for Structural Genomics.]]
  </jmolCheckbox>
[[Category: 2648890]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vll ConSurf].
[[Category: Af1665]]
<div style="clear:both"></div>
[[Category: Alanine dehydrogenase]]
== References ==
[[Category: Jcsg]]
<references/>
[[Category: Joint center for structural genomic]]
__TOC__
[[Category: Protein structure initiative]]
</StructureSection>
[[Category: Psi]]
[[Category: Archaeoglobus fulgidus DSM 4304]]
[[Category: Structural genomic]]
[[Category: Large Structures]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 12:41:11 2008''
Retrieved from "https://proteopedia.org/1vll"