9ofa: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
m Protected "9ofa" [edit=sysop:move=sysop]
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 9ofa is ON HOLD
==The structure of a Fungal Cyanide Hydratase from Gloeocercospora sorghi==
<StructureSection load='9ofa' size='340' side='right'caption='[[9ofa]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ofa]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Microdochium_sorghi Microdochium sorghi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9OFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9OFA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ofa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ofa OCA], [https://pdbe.org/9ofa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ofa RCSB], [https://www.ebi.ac.uk/pdbsum/9ofa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ofa ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Cyanide is widely used in industries due to its affinity for metals, a property that also underlies its toxicity. Industries, therefore, must reduce cyanide concentration before the final disposal of wastewater. Physical, chemical, and biological methods have been developed for this; however, knowledge about the structure of enzymes involved in cyanide degradation remains limited. Structural characterization of these proteins could facilitate the development of enzymes with enhanced bioremediation potential. Here, we present the single-particle cryo-electron microscopy structures of a cyanide dihydratase from Bacillus safensis and a cyanide hydratase from Gloeocercospora sorghi at 2.2 A and 2.0 A resolution, respectively. We provide a comprehensive description and comparative analysis alongside all previously determined nitrilase structures. Importantly, our full-length structures reveal new features in the C-terminal as well as specific intermolecular interactions between protomer interfaces and within the helix lumen. Finally, our findings offer insights into the reaction mechanisms of these two enzymes.


Authors: Santiago, J.A., Valeria, V.F., Andrea, B.F., Shaker, S.F.
The single-particle cryo-EM structures of a bacterial cyanide dihydratase and a fungal cyanide hydratase.,Justo Arevalo S, Valle-Riestra Felice V, Barahona Acuna M, Ordinola Flores K, Quinones Aguilar M, Balan A, Farah CS Structure. 2026 Feb 17:S0969-2126(26)00011-0. doi: 10.1016/j.str.2026.01.009. PMID:41709456<ref>PMID:41709456</ref>


Description: The structure of a Fungal Cyanide Hydratase from Gloeocercospora sorghi
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
[[Category: Unreleased Structures]]
</div>
[[Category: Valeria, V.F]]
<div class="pdbe-citations 9ofa" style="background-color:#fffaf0;"></div>
[[Category: Shaker, S.F]]
== References ==
[[Category: Andrea, B.F]]
<references/>
[[Category: Santiago, J.A]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Microdochium sorghi]]
[[Category: Balan A]]
[[Category: Farah CS]]
[[Category: Justo Arevalo S]]
[[Category: Valle-Riestra F V]]
Retrieved from "https://proteopedia.org/9ofa"