1z6x: Difference between revisions
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New page: left|200px<br /> <applet load="1z6x" size="450" color="white" frame="true" align="right" spinBox="true" caption="1z6x, resolution 2.70Å" /> '''Structure Of Human ... |
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== | ==Structure Of Human ADP-Ribosylation Factor 4== | ||
<StructureSection load='1z6x' size='340' side='right'caption='[[1z6x]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1z6x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z6X FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z6x OCA], [https://pdbe.org/1z6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z6x RCSB], [https://www.ebi.ac.uk/pdbsum/1z6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z6x ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ARF4_HUMAN ARF4_HUMAN] GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/1z6x_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z6x ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith C]] | ||
[[Category: Atanassova | [[Category: Atanassova A]] | ||
[[Category: Bochkarev | [[Category: Bochkarev A]] | ||
[[Category: Choe | [[Category: Choe J]] | ||
[[Category: Edwards | [[Category: Edwards A]] | ||
[[Category: Park | [[Category: Park H]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sundstrom | |||
Latest revision as of 07:04, 23 August 2023
Structure Of Human ADP-Ribosylation Factor 4
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