9ogy: Difference between revisions
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==Megrivirus E 3' internal ribosome entry site (IRES) RNA core region bound to rabbit ribosome== | |||
<StructureSection load='9ogy' size='340' side='right'caption='[[9ogy]], [[Resolution|resolution]] 3.28Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9ogy]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Megrivirus_E Megrivirus E] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9OGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9OGY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.28Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ogy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ogy OCA], [https://pdbe.org/9ogy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ogy RCSB], [https://www.ebi.ac.uk/pdbsum/9ogy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ogy ProSAT]</span></td></tr> | ||
[[Category: Kieft | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/RSSA_RABIT RSSA_RABIT] Required for the assembly and/or stability of the 40S ribosomal subunit (PubMed:23873042, PubMed:25601755). Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (PubMed:23873042, PubMed:25601755). Also functions as a cell surface receptor for laminin (By similarity). Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways (By similarity). May play a role in cell fate determination and tissue morphogenesis (By similarity). Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA (By similarity).[HAMAP-Rule:MF_03016]<ref>PMID:23873042</ref> <ref>PMID:25601755</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Megrivirus E]] | |||
[[Category: Oryctolagus cuniculus]] | |||
[[Category: Kieft JS]] | |||
[[Category: Sherlock ME]] | |||
Latest revision as of 11:11, 10 February 2026
Megrivirus E 3' internal ribosome entry site (IRES) RNA core region bound to rabbit ribosome
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