9v2n: Difference between revisions

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'''Unreleased structure'''


The entry 9v2n is ON HOLD
==Macimorelin bound growth hormone secretagogue receptor in complex with Gq==
 
<StructureSection load='9v2n' size='340' side='right'caption='[[9v2n]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
Authors: Wang, R., Sun, J., Liu, H., Guo, S., Zhang, Y., Hu, W., Wang, J., Liu, H., Zhuang, Y., Jiang, Y., Xie, X., Xu, H., Wang, Y.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9v2n]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9V2N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9V2N FirstGlance]. <br>
Description: Macimorelin bound growth hormone secretagogue receptor in complex with Gq
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.63&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EQV:2-azanyl-~{N}-[(2~{R})-1-[[(1~{R})-1-formamido-2-(1~{H}-indol-3-yl)ethyl]amino]-3-(1~{H}-indol-3-yl)-1-oxidanylidene-propan-2-yl]-2-methyl-propanamide'>A1EQV</scene></td></tr>
[[Category: Jiang, Y]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9v2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9v2n OCA], [https://pdbe.org/9v2n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9v2n RCSB], [https://www.ebi.ac.uk/pdbsum/9v2n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9v2n ProSAT]</span></td></tr>
[[Category: Liu, H]]
</table>
[[Category: Sun, J]]
== Function ==
[[Category: Wang, J]]
[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
[[Category: Hu, W]]
== References ==
[[Category: Wang, R]]
<references/>
[[Category: Zhuang, Y]]
__TOC__
[[Category: Zhang, Y]]
</StructureSection>
[[Category: Xu, H]]
[[Category: Escherichia coli]]
[[Category: Xie, X]]
[[Category: Homo sapiens]]
[[Category: Wang, Y]]
[[Category: Lama glama]]
[[Category: Guo, S]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Guo S]]
[[Category: Hu W]]
[[Category: Jiang Y]]
[[Category: Liu H]]
[[Category: Sun J]]
[[Category: Wang J]]
[[Category: Wang R]]
[[Category: Wang Y]]
[[Category: Xie X]]
[[Category: Xu H]]
[[Category: Zhang Y]]
[[Category: Zhuang Y]]
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