9kq3: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 9kq3 is ~~ON HOLD~~

==Cryo-EM structure of Saccharomyces cerevisiae Mitochondrial Respiratory Complex II in pydiflumetofen-bound state==

~~Authors~~: Li, Z.W., Ye, Y., ~~Yang~~, G.F.

== Structural highlights ==

<table><tr><td colspan='2'>[[9kq3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KQ3 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9KQ3 FirstGlance].

~~Description~~: ~~Cryo-EM structure~~ of ~~Saccharomyces cerevisiae Mitochondrial Respiratory Complex~~ II ~~in pydiflumetofen~~-bound ~~state~~

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.23Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EE4:3-[bis(fluoranyl)methyl]-~{N}-methoxy-1-methyl-~{N}-[(2~{S})-1-[2,4,6-tris(chloranyl)phenyl]propan-2-yl]pyrazole-4-carboxamide'>A1EE4</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=PEE:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>PEE</scene></td></tr>

[[Category: ~~Ye, Y~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9kq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kq3 OCA], [https://pdbe.org/9kq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kq3 RCSB], [https://www.ebi.ac.uk/pdbsum/9kq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kq3 ProSAT]</td></tr>

[[Category: Li~~, Z.W~~]]

</table>

[[Category: Yang~~, G.F~~]]

== Function ==

[https://www.uniprot.org/uniprot/SDHA_YEAST SDHA_YEAST] Catalytic subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH1 and SDH2 form the catalytic dimer. Electrons flow from succinate to the FAD bound to SDH1, and sequentially through the iron-sulfur clusters bound to SDH2 and enter the membrane dimer formed by SDH3 and SDH4.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Saccharomyces cerevisiae]]

[[Category: Li ZW]]

[[Category: Yang GF]]

[[Category: Ye Y]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9kq3 is ON HOLD
+==Cryo-EM structure of Saccharomyces cerevisiae Mitochondrial Respiratory Complex II in pydiflumetofen-bound state==
+<StructureSection load='9kq3' size='340' side='right'caption='[[9kq3]], [[Resolution|resolution]] 3.23&Aring;' scene=''>
-Authors: Li, Z.W., Ye, Y., Yang, G.F.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9kq3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KQ3 FirstGlance]. <br>
-Description: Cryo-EM structure of Saccharomyces cerevisiae Mitochondrial Respiratory Complex II in pydiflumetofen-bound state
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.23&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EE4:3-[bis(fluoranyl)methyl]-~{N}-methoxy-1-methyl-~{N}-[(2~{S})-1-[2,4,6-tris(chloranyl)phenyl]propan-2-yl]pyrazole-4-carboxamide'>A1EE4</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=PEE:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>PEE</scene></td></tr>
-[[Category: Ye, Y]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kq3 OCA], [https://pdbe.org/9kq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kq3 RCSB], [https://www.ebi.ac.uk/pdbsum/9kq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kq3 ProSAT]</span></td></tr>
-[[Category: Li, Z.W]]
+</table>
-[[Category: Yang, G.F]]
+== Function ==
+[https://www.uniprot.org/uniprot/SDHA_YEAST SDHA_YEAST] Catalytic subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH1 and SDH2 form the catalytic dimer. Electrons flow from succinate to the FAD bound to SDH1, and sequentially through the iron-sulfur clusters bound to SDH2 and enter the membrane dimer formed by SDH3 and SDH4.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Saccharomyces cerevisiae]]
+[[Category: Li ZW]]
+[[Category: Yang GF]]
+[[Category: Ye Y]]