9p05: Difference between revisions

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New page: '''Unreleased structure''' The entry 9p05 is ON HOLD Authors: Goldberg, J. Description: Structure of human Sec23a/Sec24a/Sec22b bound to CPD11 Category: Unreleased Structures [[Cat...
 
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'''Unreleased structure'''


The entry 9p05 is ON HOLD
==Structure of human Sec23a/Sec24a/Sec22b bound to CPD11==
 
<StructureSection load='9p05' size='340' side='right'caption='[[9p05]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
Authors: Goldberg, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9p05]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9P05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9P05 FirstGlance]. <br>
Description: Structure of human Sec23a/Sec24a/Sec22b bound to CPD11
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EQA:(2~{R},3~{R})-2-[(3-hydroxyphenyl)methyl]-3-phenyl-cyclopropane-1,1-dicarboxylic+acid'>A1EQA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Goldberg, J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9p05 OCA], [https://pdbe.org/9p05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9p05 RCSB], [https://www.ebi.ac.uk/pdbsum/9p05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9p05 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/SC23A_HUMAN SC23A_HUMAN] Defects in SEC23A are the cause of craniolenticulosutural dysplasia (CLSD) [MIM:[https://omim.org/entry/607812 607812]; also known as cranio-lenticulo-sutural dysplasia. CLSD is an autosomal recessive syndrome characterized by late-closing fontanels, sutural cataracts, facial dysmorphisms and skeletal defects.<ref>PMID:16980979</ref>
== Function ==
[https://www.uniprot.org/uniprot/SC23A_HUMAN SC23A_HUMAN] Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Goldberg J]]
Retrieved from "https://proteopedia.org/9p05"