9vft: Difference between revisions
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New page: '''Unreleased structure''' The entry 9vft is ON HOLD Authors: Ke, X., Li, X., Liu, Z., Liu, K., Yan, X., Shu, B., Zhang, C. Description: Structure of mature CVA6 virus complexed with 3... |
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==Structure of mature CVA6 virus complexed with 3H7 Fab== | |||
<StructureSection load='9vft' size='340' side='right'caption='[[9vft]], [[Resolution|resolution]] 2.59Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9vft]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxsackievirus_A6 Coxsackievirus A6] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9VFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9VFT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.59Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9vft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9vft OCA], [https://pdbe.org/9vft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9vft RCSB], [https://www.ebi.ac.uk/pdbsum/9vft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9vft ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Li | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/E3VJS6_9ENTO E3VJS6_9ENTO] Component of immature procapsids, which is cleaved into capsid proteins VP4 and VP2 after maturation. Allows the capsid to remain inactive before the maturation step.[ARBA:ARBA00045749] Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome.[ARBA:ARBA00045131] Lies on the inner surface of the capsid shell. After binding to the host receptor, the capsid undergoes conformational changes. Capsid protein VP4 is released, Capsid protein VP1 N-terminus is externalized, and together, they shape a pore in the host membrane through which the viral genome is translocated into the host cell cytoplasm.[ARBA:ARBA00045311] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Yan | [[Category: Coxsackievirus A6]] | ||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Ke X]] | |||
[[Category: Li X]] | |||
[[Category: Liu K]] | |||
[[Category: Liu Z]] | |||
[[Category: Shu B]] | |||
[[Category: Yan X]] | |||
[[Category: Zhang C]] | |||
Latest revision as of 07:54, 19 November 2025
Structure of mature CVA6 virus complexed with 3H7 Fab
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