9rp1: Difference between revisions
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New page: '''Unreleased structure''' The entry 9rp1 is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Ensemble refined structure of CotB2 in complex with alendronate== | |||
<StructureSection load='9rp1' size='340' side='right'caption='[[9rp1]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9rp1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_melanosporofaciens Streptomyces melanosporofaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RP1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RP1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AHD:4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE'>AHD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rp1 OCA], [https://pdbe.org/9rp1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rp1 RCSB], [https://www.ebi.ac.uk/pdbsum/9rp1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rp1 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/COTB2_STRMJ COTB2_STRMJ] Catalyzes the cyclization of the linear isoprenoid intermediate geranylgeranyl diphosphate to tricycclic cyclooctat-9-en-7-ol in the cyclooctatin biosynthesis pathway. Cyclooctatin is a potent inhibitor of lysophospholipase.<ref>PMID:19635410</ref> <ref>PMID:24914964</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Streptomyces melanosporofaciens]] | |||
[[Category: Helmer CPO]] | |||
[[Category: Loll B]] | |||
Latest revision as of 08:00, 25 February 2026
Ensemble refined structure of CotB2 in complex with alendronate
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