9rx4: Difference between revisions

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'''Unreleased structure'''


The entry 9rx4 is ON HOLD
==VPS34-CI bound to NRBF2 and RAB1A==
 
<StructureSection load='9rx4' size='340' side='right'caption='[[9rx4]], [[Resolution|resolution]] 3.67&Aring;' scene=''>
Authors: Spokaite, S., Ohashi, Y., Dessus, A.N., Bourguet, M., Williams, R.L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9rx4]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RX4 FirstGlance]. <br>
Description: VPS34-CI bound to NRBF2 and RAB1A
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.67&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Dessus, A.N]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rx4 OCA], [https://pdbe.org/9rx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rx4 RCSB], [https://www.ebi.ac.uk/pdbsum/9rx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rx4 ProSAT]</span></td></tr>
[[Category: Williams, R.L]]
</table>
[[Category: Ohashi, Y]]
== Function ==
[[Category: Spokaite, S]]
[https://www.uniprot.org/uniprot/PK3C3_HUMAN PK3C3_HUMAN] Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.<ref>PMID:7628435</ref> <ref>PMID:14617358</ref> <ref>PMID:20208530</ref>
[[Category: Bourguet, M]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bourguet M]]
[[Category: Dessus AN]]
[[Category: Ohashi Y]]
[[Category: Spokaite S]]
[[Category: Williams RL]]

Latest revision as of 16:17, 22 July 2026

VPS34-CI bound to NRBF2 and RAB1A

9rx4, resolution 3.67Å

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