9l9b: Difference between revisions
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The | ==The crystal structure of human RyR3 Repeat12 domain in complex with Dantrolene and ADP== | ||
<StructureSection load='9l9b' size='340' side='right'caption='[[9l9b]], [[Resolution|resolution]] 2.84Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9l9b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9L9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9L9B FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.84Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=U1C:1-[(Z)-{[5-(4-nitrophenyl)furan-2-yl]methylidene}amino]imidazolidine-2,4-dione'>U1C</scene></td></tr> | ||
[[Category: Hadiatullah | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9l9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9l9b OCA], [https://pdbe.org/9l9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9l9b RCSB], [https://www.ebi.ac.uk/pdbsum/9l9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l9b ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[https://www.uniprot.org/uniprot/RYR3_HUMAN RYR3_HUMAN] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Contributes to cellular calcium ion homeostasis (By similarity). Plays a role in cellular calcium signaling.<ref>PMID:12354756</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Hadiatullah H]] | |||
[[Category: Lin L]] | |||
[[Category: Yuchi Z]] | |||
Latest revision as of 09:17, 22 October 2025
The crystal structure of human RyR3 Repeat12 domain in complex with Dantrolene and ADP
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