9w2j: Difference between revisions
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New page: '''Unreleased structure''' The entry 9w2j is ON HOLD Authors: Ren, Y., Pavlovskyil, A., Liu, X., Gerhart-Hines, Z. Description: Cryo-EM structure of Peptide 383 (P383)-bound neurokinin... |
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==Cryo-EM structure of Peptide 383 (P383)-bound neurokinin 2 receptor (NK2R) in complex with miniGs/q70== | |||
<StructureSection load='9w2j' size='340' side='right'caption='[[9w2j]], [[Resolution|resolution]] 2.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9w2j]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9W2J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9W2J FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.82Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EUR:(2~{S})-2-azanyl-4-methoxy-butanoic+acid'>A1EUR</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9w2j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9w2j OCA], [https://pdbe.org/9w2j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9w2j RCSB], [https://www.ebi.ac.uk/pdbsum/9w2j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9w2j ProSAT]</span></td></tr> | ||
[[Category: Gerhart-Hines | </table> | ||
[[Category: Liu | == Function == | ||
[[Category: Ren | [https://www.uniprot.org/uniprot/GBG2_HUMAN GBG2_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity). | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Gerhart-Hines Z]] | |||
[[Category: Liu X]] | |||
[[Category: Pavlovskyil A]] | |||
[[Category: Ren Y]] | |||
Latest revision as of 07:25, 17 June 2026
Cryo-EM structure of Peptide 383 (P383)-bound neurokinin 2 receptor (NK2R) in complex with miniGs/q70
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