9w3z: Difference between revisions
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==Cryo-EM structure of the 4:4 Lac1-Lip1 complex== | |||
<StructureSection load='9w3z' size='340' side='right'caption='[[9w3z]], [[Resolution|resolution]] 3.36Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9w3z]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9W3Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9W3Z FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.36Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9w3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9w3z OCA], [https://pdbe.org/9w3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9w3z RCSB], [https://www.ebi.ac.uk/pdbsum/9w3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9w3z ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LAC1_YEAST LAC1_YEAST] Component of the ceramide synthase complex that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward hexacosanoyl-CoA (C26:0-CoA) (PubMed:11694577, PubMed:15692566). N-acylates sphinganine and phytosphingosine bases to form dihydroceramides and phytoceramides, respectively (PubMed:11694577, PubMed:15692566). Redundant with LAG1. Facilitates ER-to-Golgi transport of GPI-anchored proteins.<ref>PMID:10198056</ref> <ref>PMID:11387200</ref> <ref>PMID:11694577</ref> <ref>PMID:15692566</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Gong X]] | |||
[[Category: Xie T]] | |||
Latest revision as of 06:33, 8 April 2026
Cryo-EM structure of the 4:4 Lac1-Lip1 complex
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