9wbp: Difference between revisions

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New page: '''Unreleased structure''' The entry 9wbp is ON HOLD Authors: Yadav, V.K., Bhattacharyya, S. Description: Crystal Structure of Pseudomonas aeruginosa SuhB in complex with Adenosine 2''...
 
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'''Unreleased structure'''


The entry 9wbp is ON HOLD
==Crystal Structure of Pseudomonas aeruginosa SuhB in complex with Adenosine 2'-monophosphate==
 
<StructureSection load='9wbp' size='340' side='right'caption='[[9wbp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
Authors: Yadav, V.K., Bhattacharyya, S.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9wbp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WBP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WBP FirstGlance]. <br>
Description: Crystal Structure of Pseudomonas aeruginosa SuhB in complex with Adenosine 2''-monophosphate
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2AM:ADENOSINE-2-MONOPHOSPHATE'>2AM</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
[[Category: Yadav, V.K]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wbp OCA], [https://pdbe.org/9wbp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wbp RCSB], [https://www.ebi.ac.uk/pdbsum/9wbp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wbp ProSAT]</span></td></tr>
[[Category: Bhattacharyya, S]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/SUHB_PSEAE SUHB_PSEAE] Part of the processive rRNA transcription and antitermination complex (rrnTAC). The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNA polymerase (RNAP). It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis. This subunit may play a central role in organizing the structure.[UniProtKB:P0ADG4]  A ribosome-associated protein, deletion of which alters the expression of 494 genes, suggesting a role in global gene regulation (PubMed:26179141). Involved in control of pathogenesis-related genes. Required for the activation of virulence factors associated with acute infections (type 3 secretion system, T3SS) while suppressing virulence factors associated with chronic infections (biofilm formation and type 6 secretion system, T6SS). It probably acts at a post-transcriptional level (PubMed:24169572).<ref>PMID:24169572</ref> <ref>PMID:26179141</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Bhattacharyya S]]
[[Category: Yadav VK]]
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