9q3r: Difference between revisions

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'''Unreleased structure'''


The entry 9q3r is ON HOLD
==Cryo-EM structure of the Escherichia coli 70S ribosome bound to mRNA, P-site fMet-tRNAfMet, glycyl-tRNAGly in A/T conformation, EF-Tu-GDPCP, and bottromycin at 1.99A resolution==
 
<StructureSection load='9q3r' size='340' side='right'caption='[[9q3r]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
Authors: Travin, D.Y., Basu, R.S., Paranjpe, M., Klepacki, D., Zhurakovskaya, A.I., Vazquez-Laslop, N., Mankin, A.S., Polikanov, Y.S., Gagnon, M.G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9q3r]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Q3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Q3R FirstGlance]. <br>
Description: Cryo-EM structure of the Escherichia coli 70S ribosome bound to mRNA, P-site fMet-tRNAfMet, glycyl-tRNAGly in A/T conformation, EF-Tu-GDPCP, and bottromycin at 2.04A resolution
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MG:1N-METHYLGUANOSINE-5-MONOPHOSPHATE'>1MG</scene>, <scene name='pdbligand=2MA:2-METHYLADENOSINE-5-MONOPHOSPHATE'>2MA</scene>, <scene name='pdbligand=2MG:2N-METHYLGUANOSINE-5-MONOPHOSPHATE'>2MG</scene>, <scene name='pdbligand=3TD:(1S)-1,4-ANHYDRO-1-(3-METHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)-5-O-PHOSPHONO-D-RIBITOL'>3TD</scene>, <scene name='pdbligand=4D4:(2S,3R)-2-AZANYL-5-CARBAMIMIDAMIDO-3-OXIDANYL-PENTANOIC+ACID'>4D4</scene>, <scene name='pdbligand=4OC:4N,O2-METHYLCYTIDINE-5-MONOPHOSPHATE'>4OC</scene>, <scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=6MZ:N6-METHYLADENOSINE-5-MONOPHOSPHATE'>6MZ</scene>, <scene name='pdbligand=D2T:(3R)-3-(METHYLSULFANYL)-L-ASPARTIC+ACID'>D2T</scene>, <scene name='pdbligand=G7M:N7-METHYL-GUANOSINE-5-MONOPHOSPHATE'>G7M</scene>, <scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=L3X:3-deoxy-3-(glycylamino)adenosine+5-(dihydrogen+phosphate)'>L3X</scene>, <scene name='pdbligand=M3O:3-O-(N-FORMYL-L-METHIONYL)ADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>M3O</scene>, <scene name='pdbligand=MA6:6N-DIMETHYLADENOSINE-5-MONOPHOSHATE'>MA6</scene>, <scene name='pdbligand=MEQ:N5-METHYLGLUTAMINE'>MEQ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MQH:methyl+(3~{R})-3-[[(2~{S},3~{S})-2-[[(2~{S})-2-[(~{E})-[(6~{S},9~{S},12~{S},13~{R})-6-~{tert}-butyl-13-methyl-2,8,11-tris(oxidanylidene)-9-propan-2-yl-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-5-ylidene]amino]-3,3-dimethyl-butanoyl]amino]-3-phenyl-butanoyl]amino]-3-(1,3-thiazol-2-yl)propanoate'>MQH</scene>, <scene name='pdbligand=MS6:(2S)-2-amino-4-(methylsulfanyl)butane-1-thiol'>MS6</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Zhurakovskaya, A.I]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9q3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9q3r OCA], [https://pdbe.org/9q3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9q3r RCSB], [https://www.ebi.ac.uk/pdbsum/9q3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9q3r ProSAT]</span></td></tr>
[[Category: Polikanov, Y.S]]
</table>
[[Category: Basu, R.S]]
== Function ==
[[Category: Mankin, A.S]]
[https://www.uniprot.org/uniprot/J7QM75_ECOLX J7QM75_ECOLX]
[[Category: Vazquez-Laslop, N]]
__TOC__
[[Category: Klepacki, D]]
</StructureSection>
[[Category: Paranjpe, M]]
[[Category: Escherichia coli]]
[[Category: Travin, D.Y]]
[[Category: Large Structures]]
[[Category: Gagnon, M.G]]
[[Category: Basu RS]]
[[Category: Gagnon MG]]
[[Category: Klepacki D]]
[[Category: Mankin AS]]
[[Category: Paranjpe M]]
[[Category: Polikanov YS]]
[[Category: Travin DY]]
[[Category: Vazquez-Laslop N]]
[[Category: Zhurakovskaya AI]]
Retrieved from "https://proteopedia.org/9q3r"