9wd7: Difference between revisions

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'''Unreleased structure'''


The entry 9wd7 is ON HOLD
==GMPCPP-stabilizsd human alpha1A/beta3 microtubule==
 
<StructureSection load='9wd7' size='340' side='right'caption='[[9wd7]], [[Resolution|resolution]] 2.34&Aring;' scene=''>
Authors: Ti, S.C., Luo, J.Y., Khoo, C.J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9wd7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WD7 FirstGlance]. <br>
Description: GMPCPP-stabilizsd human alpha1A/beta3 microtubule
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.34&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Khoo, C.J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wd7 OCA], [https://pdbe.org/9wd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wd7 RCSB], [https://www.ebi.ac.uk/pdbsum/9wd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wd7 ProSAT]</span></td></tr>
[[Category: Ti, S.C]]
</table>
[[Category: Luo, J.Y]]
== Disease ==
[https://www.uniprot.org/uniprot/TBA1A_HUMAN TBA1A_HUMAN] Lissencephaly due to TUBA1A mutation. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/TBA1A_HUMAN TBA1A_HUMAN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Khoo CJ]]
[[Category: Luo JY]]
[[Category: Ti SC]]