9y78: Difference between revisions
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==Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA in complex with UMN141== | |||
<StructureSection load='9y78' size='340' side='right'caption='[[9y78]], [[Resolution|resolution]] 2.54Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9y78]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Y78 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Y78 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.54Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1CSZ:[(7~{S},9~{E},11~{S},12~{R},13~{S},14~{R},15~{R},16~{R},17~{S},18~{S},19~{E},21~{Z})-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1-(2-methylpropyl)-2,15,17-tris(oxidanyl)-6,23,32-tris(oxidanylidene)spiro[8,33-dioxa-24,27,29-triazapentacyclo[23.6.1.1^{4,7}.0^{5,31}.0^{26,30}]tritriaconta-1,3,5(31),9,19,21,25,29-octaene-28,4-piperidine]-13-yl]+~{N}-(5,6-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)carbamate'>A1CSZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9y78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9y78 OCA], [https://pdbe.org/9y78 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9y78 RCSB], [https://www.ebi.ac.uk/pdbsum/9y78 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9y78 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RPOA_MYCTU RPOA_MYCTU] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00059]<ref>PMID:22570422</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Ebright RH]] | |||
[[Category: You LL]] | |||
Latest revision as of 09:47, 30 September 2026
Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA in complex with UMN141
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