9y7m: Difference between revisions
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New page: '''Unreleased structure''' The entry 9y7m is ON HOLD Authors: Description: Category: Unreleased Structures |
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==HCMV Protease in complex with Fab5 - Class 2== | |||
<StructureSection load='9y7m' size='340' side='right'caption='[[9y7m]], [[Resolution|resolution]] 2.57Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9y7m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Cytomegalovirus Cytomegalovirus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Y7M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Y7M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.57Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9y7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9y7m OCA], [https://pdbe.org/9y7m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9y7m RCSB], [https://www.ebi.ac.uk/pdbsum/9y7m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9y7m ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SCAF_HCMVA SCAF_HCMVA] Capsid scaffolding protein acts as a scaffold protein by binding major capsid protein UL86 in the cytoplasm, inducing the nuclear localization of both proteins. Multimerizes in the nucleus such as protein UL86 forms the icosahedral T=16 capsid. Autocatalytic cleavage releases the assembly protein, and subsequently abolishes interaction with major capsid protein UL86. Cleavages products are evicted from the capsid before or during DNA packaging (By similarity). Assemblin is a protease essential for virion assembly in the nucleus. Catalyzes the cleavage of the assembly protein after complete capsid formation. Assemblin and cleavages products are evicted from the capsid before or during DNA packaging (By similarity). Assembly protein plays a major role in capsid assembly. Acts as a scaffold protein by binding major capsid protein UL86. Multimerizes in the nucleus such as protein UL86 forms the icosahedral T=16 capsid. Cleaved by assemblin after capsid completion. The cleavages products are evicted from the capsid before or during DNA packaging (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Cytomegalovirus]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Bohn MF]] | |||
[[Category: Cheng Y]] | |||
[[Category: Craik C]] | |||
[[Category: Detomasi TC]] | |||
[[Category: Hulce KR]] | |||
[[Category: Norman J]] | |||
[[Category: Rohweder PJ]] | |||
[[Category: Zimanyi M]] | |||
Latest revision as of 05:13, 27 May 2026
HCMV Protease in complex with Fab5 - Class 2
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