9xwt: Difference between revisions
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==Phosphoglycerate mutase 1 complexed with a novel scaffold inhibitor== | |||
<StructureSection load='9xwt' size='340' side='right'caption='[[9xwt]], [[Resolution|resolution]] 2.28Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9xwt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9XWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9XWT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1E1M:7-bromanyl-5-chloranyl-1~{H}-indole-2-carboxylic+acid'>A1E1M</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9xwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9xwt OCA], [https://pdbe.org/9xwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9xwt RCSB], [https://www.ebi.ac.uk/pdbsum/9xwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9xwt ProSAT]</span></td></tr> | ||
[[Category: Li | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Li S]] | |||
[[Category: Zhou L]] | |||
Latest revision as of 14:48, 10 February 2026
Phosphoglycerate mutase 1 complexed with a novel scaffold inhibitor
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