9zhm: Difference between revisions
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New page: '''Unreleased structure''' The entry 9zhm is ON HOLD Authors: Fried, S.D.E., Boxer, S.G. Description: M20E Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine... |
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==M20E Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)== | |||
<StructureSection load='9zhm' size='340' side='right'caption='[[9zhm]], [[Resolution|resolution]] 1.07Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9zhm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZHM FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.07Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
[[Category: Boxer | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zhm OCA], [https://pdbe.org/9zhm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zhm RCSB], [https://www.ebi.ac.uk/pdbsum/9zhm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zhm ProSAT]</span></td></tr> | ||
[[Category: Fried | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Boxer SG]] | |||
[[Category: Fried SDE]] | |||
Latest revision as of 16:31, 22 July 2026
M20E Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)
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