9zn0: Difference between revisions

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'''Unreleased structure'''


The entry 9zn0 is ON HOLD
==Crystal structure of the Commd10 S50E HN domain mutant in domain swapped conformation==
 
<StructureSection load='9zn0' size='340' side='right'caption='[[9zn0]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
Authors: Collins, B.M., Healy, M.D., Liu, M., Hall, R.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9zn0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZN0 FirstGlance]. <br>
Description: Crystal structure of the Commd10 S50E HN domain mutant in domain swapped conformation
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LEA:PENTANOIC+ACID'>LEA</scene></td></tr>
[[Category: Collins, B.M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zn0 OCA], [https://pdbe.org/9zn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zn0 RCSB], [https://www.ebi.ac.uk/pdbsum/9zn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zn0 ProSAT]</span></td></tr>
[[Category: Hall, R]]
</table>
[[Category: Healy, M.D]]
== Function ==
[[Category: Liu, M]]
[https://www.uniprot.org/uniprot/COMDA_HUMAN COMDA_HUMAN] Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (PubMed:37172566, PubMed:38459129). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966).<ref>PMID:15799966</ref> <ref>PMID:37172566</ref> <ref>PMID:38459129</ref> <ref>PMID:21778237</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Collins BM]]
[[Category: Hall R]]
[[Category: Healy MD]]
[[Category: Liu M]]
Retrieved from "https://proteopedia.org/9zn0"