9zeb: Difference between revisions
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==Cryo-EM structure of the TREX-2.1 complex (Thp3/Csn12/Sem1) bound to the DEAD-box ATPase Sub2== | |||
<StructureSection load='9zeb' size='340' side='right'caption='[[9zeb]], [[Resolution|resolution]] 3.72Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9zeb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZEB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZEB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.72Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AMM:(2~{S})-2-azanyl-3-[4-(phenylmethyl)phenyl]propanoic+acid'>A1AMM</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zeb OCA], [https://pdbe.org/9zeb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zeb RCSB], [https://www.ebi.ac.uk/pdbsum/9zeb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zeb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/THP3_YEAST THP3_YEAST] Forms a complex with CSN12 that is recruited to transcribed genes and required for transcription elongation. May also be involved in pre-mRNA splicing.<ref>PMID:19061648</ref> <ref>PMID:19289793</ref> <ref>PMID:21149575</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Angelos AE]] | |||
[[Category: Clarke BP]] | |||
[[Category: Ren Y]] | |||
[[Category: Xie Y]] | |||
Latest revision as of 09:50, 30 September 2026
Cryo-EM structure of the TREX-2.1 complex (Thp3/Csn12/Sem1) bound to the DEAD-box ATPase Sub2
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