9zww: Difference between revisions

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New page: '''Unreleased structure''' The entry 9zww is ON HOLD Authors: Wang, H., Stanley, R.E. Description: Crystal structure of the N4BP2 polynucleotide kinase (PNK) domain in complex with ATP...
 
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'''Unreleased structure'''


The entry 9zww is ON HOLD
==Crystal structure of the N4BP2 polynucleotide kinase domain complexed with ATP, Mg, and the trinucleotide substrate CCA.==
 
<StructureSection load='9zww' size='340' side='right'caption='[[9zww]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
Authors: Wang, H., Stanley, R.E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9zww]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZWW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZWW FirstGlance]. <br>
Description: Crystal structure of the N4BP2 polynucleotide kinase (PNK) domain in complex with ATP, Mg, and the trinucleotide CCA, capturing the pre-reactant state.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Wang, H]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zww OCA], [https://pdbe.org/9zww PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zww RCSB], [https://www.ebi.ac.uk/pdbsum/9zww PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zww ProSAT]</span></td></tr>
[[Category: Stanley, R.E]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/N4BP2_HUMAN N4BP2_HUMAN] Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination.<ref>PMID:12730195</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Stanley RE]]
[[Category: Wang H]]

Latest revision as of 16:37, 25 September 2026

Crystal structure of the N4BP2 polynucleotide kinase domain complexed with ATP, Mg, and the trinucleotide substrate CCA.

9zww, resolution 1.85Å

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