User:Wayne Decatur/Hsp90 Structures with client proteins: Difference between revisions

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This page is meant to highlight structures particularly insightful into the structural basis of Hsp90 interacting with client proteins and associated factors, such as co-chaperones & phosphatases.
This page is meant to highlight structures particularly insightful into the structural basis of Hsp90 interacting with client proteins and associated factors, such as cochaperones & phosphatases.


<StructureSection load='1stp' size='340' align='right' caption='' scene=''>
== Function ==


== Disease ==
== Model Client: Kinases ==
<StructureSection load='8gft' size='340' align='right' caption='' scene=''></StructureSection>


== Relevance ==
* Hsp90 with Craf kinase, cochaperone Cdc37, and Phosphatase PP5. (8GFT)
* Hsp90 with Craf kinase and cochaperone Cdc37.
* Hsp90 with Cdk4 kinase and cochaperone Cdc37.


== Structural highlights ==
== Model Client: Glucocorticoid Receptor (GR) ==
<StructureSection load='1d66' size='340' align='right' caption='' scene=''></StructureSection>
 
 
* Hsp90 with GR, Hsp70, and Stress-induced-phosphoprotein 1 / Hsp70-Hsp90 organising protein (Hop). (7KW7)
* Hsp90 with GR and immunophilin FKBP51 (peptidyl-prolyl isomerase) (8ffw)
* Hsp90 with GR and immunophilin FKBP52 (peptidyl-prolyl isomerase) (8ffv)
* Hsp90 with GR and p23 cochaperone. (7KRJ)
 
 
 
== See Also ==


This is a sample scene created with SAT to <scene name='10/1070530/1stp_coloerd/1'>color</scene> by Group, and another to make <scene name='10/1070530/1stp_transparency/1'>a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.


</StructureSection>
== References ==
== References ==
<references/>

Latest revision as of 20:14, 11 February 2026

This page is meant to highlight structures particularly insightful into the structural basis of Hsp90 interacting with client proteins and associated factors, such as cochaperones & phosphatases.


Model Client: Kinases

Drag the structure with the mouse to rotate
  • Hsp90 with Craf kinase, cochaperone Cdc37, and Phosphatase PP5. (8GFT)
  • Hsp90 with Craf kinase and cochaperone Cdc37.
  • Hsp90 with Cdk4 kinase and cochaperone Cdc37.

Model Client: Glucocorticoid Receptor (GR)

Drag the structure with the mouse to rotate


  • Hsp90 with GR, Hsp70, and Stress-induced-phosphoprotein 1 / Hsp70-Hsp90 organising protein (Hop). (7KW7)
  • Hsp90 with GR and immunophilin FKBP51 (peptidyl-prolyl isomerase) (8ffw)
  • Hsp90 with GR and immunophilin FKBP52 (peptidyl-prolyl isomerase) (8ffv)
  • Hsp90 with GR and p23 cochaperone. (7KRJ)


See Also

References

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Wayne Decatur