User:Wayne Decatur/Hsp90 Structures with client proteins: Difference between revisions
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This page is meant to highlight structures particularly insightful into the structural basis of Hsp90 interacting with client proteins and associated factors, such as | This page is meant to highlight structures particularly insightful into the structural basis of Hsp90 interacting with client proteins and associated factors, such as cochaperones & phosphatases. | ||
== | == Model Client: Kinases == | ||
<StructureSection load='8gft' size='340' align='right' caption='' scene=''></StructureSection> | |||
* Hsp90 with Craf kinase, cochaperone Cdc37, and Phosphatase PP5. (8GFT) | |||
* Hsp90 with Craf kinase and cochaperone Cdc37. | |||
* Hsp90 with Cdk4 kinase and cochaperone Cdc37. | |||
== | == Model Client: Glucocorticoid Receptor (GR) == | ||
<StructureSection load='1d66' size='340' align='right' caption='' scene=''></StructureSection> | |||
* Hsp90 with GR, Hsp70, and Stress-induced-phosphoprotein 1 / Hsp70-Hsp90 organising protein (Hop). (7KW7) | |||
* Hsp90 with GR and immunophilin FKBP51 (peptidyl-prolyl isomerase) (8ffw) | |||
* Hsp90 with GR and immunophilin FKBP52 (peptidyl-prolyl isomerase) (8ffv) | |||
* Hsp90 with GR and p23 cochaperone. (7KRJ) | |||
== See Also == | |||
== References == | == References == | ||
Latest revision as of 20:14, 11 February 2026
This page is meant to highlight structures particularly insightful into the structural basis of Hsp90 interacting with client proteins and associated factors, such as cochaperones & phosphatases.
Model Client: Kinases
|
- Hsp90 with Craf kinase, cochaperone Cdc37, and Phosphatase PP5. (8GFT)
- Hsp90 with Craf kinase and cochaperone Cdc37.
- Hsp90 with Cdk4 kinase and cochaperone Cdc37.
Model Client: Glucocorticoid Receptor (GR)
|
- Hsp90 with GR, Hsp70, and Stress-induced-phosphoprotein 1 / Hsp70-Hsp90 organising protein (Hop). (7KW7)
- Hsp90 with GR and immunophilin FKBP51 (peptidyl-prolyl isomerase) (8ffw)
- Hsp90 with GR and immunophilin FKBP52 (peptidyl-prolyl isomerase) (8ffv)
- Hsp90 with GR and p23 cochaperone. (7KRJ)